Clean-in Chane Cleanning System
|FOB Price:||US $3,000-4,500 / Piece|
|Min. Order:||1 Piece|
|Min. Order||FOB Price|
|1 Piece||US $3,000-4,500/ Piece|
|Transport Package:||Wooden Case|
|Payment Terms:||L/C, T/T, Western Union|
- Model NO.: WY-800
- Cleaning Process: Hot Water Cleaning
- Processing Procedure: Alkali Cleaning,Acid Cleaning,Hot Water Cleaning
- Process: Frozen and Chilled
- Clean Type: Clean-in-Place (Cip)
- Construction Material: SUS3014,SUS316L
- Capacity: 1-15t/H
- Origin: Wenzhou China
Clean-in-place (CIP) is a method of cleaning the interior surfaces of pipes, vessels, process equipment, filters and associated fittings, without disassembly.
Up to the 1950s, closed systems were disassembled and cleaned manually. The advent of CIP was a boon to industries that needed frequent internal cleaning of their processes. Industries that rely heavily on CIP are those requiring high levels of hygiene, and include: Dairy, beverage, brewing, processed foods, pharmaceutical, and cosmetics.
The benefit to industries that use CIP is that the cleaning is faster, less labor-intensive and more repeatable, and poses less of a chemical exposure risk to people. CIP started as a manual practice involving a balance tank, centrifugal pump, and connection to the system being cleaned. Since the 1950s, CIP has evolved to include fully automated systems with programmable logic controllers, multiple balance tanks, sensors, valves, heat exchangers, data acquisition and specially designed spray nozzle systems. Simple, manually operated CIP systems can still be found in use today.
CIP and Bioreactors, Fermentors, and Mix Vessels
CIP is commonly used for cleaning bioreactors, fermenters, mix vessels, and other equipment used in biotech manufacturing, pharmaceutical manufacturing and food and beverage manufacturing. CIP is performed to remove or obliterate previous Cell Culture batch components. It is used to remove in-process residues, control bioburden, and reduce endotoxin levels within processing equipment and systems. Residue removal is accomplished during CIP with a combination of heat, chemical action, and turbulent flow.
The Code of Federal Regulations states "Equipment and utensils shall be cleaned, maintained, and sanitized at appropriate intervals to prevent malfunctions or contamination that would alter the safety, identity, strength, quality or purity of the drug product beyond the official or other established requirements. "
Repeatable, reliable, and effective cleaning is of the utmost importance in a manufacturing facility. Cleaning procedures are validated to demonstrate that they are effective, reproducible, and under control. In order to adequately clean processing equipment, the equipment must be designed with smooth stainless steel surfaces and interconnecting piping that has cleanable joints. The chemical properties of the cleaning agents must properly interact with the chemical and physical properties of the residues being removed.
Sanitary Stainless steel CIP Cleaning System
|CIP cleaning machine confirgeration list|
|No.||item||material and size||quantity pcs/set|
|3||clean water tank||SS304||1|
|5||electric control box||1|
|8||flow distribution plate||SS304||1|
|11||CIP reflux inlet||Φ38||1|
|15||cleaning liquid outlet||Φ38||1|